Diabetes drug raises bone fracture risk in older women
Women with type 2 diabetes who take a commonly prescribed class of medications to treat insulin resistance may be at a higher risk for developing bone fractures.
Women with type 2 diabetes who take a commonly prescribed class of medications to treat insulin resistance may be at a higher risk for developing bone fractures, Henry Ford Hospital study has found.As per the study's results, after taking a thiazolidinedione (TZD) for one year, women are 50% more likely to have a bone fracture than patients not taking TZDs. And those at the greatest risk for fractures from TZD use are women older than 65."Older women are already at a higher risk of osteoporosis and osteoporosis-related fractures, which might explain why they appeared to be the most affected by TZDs," says study senior author L Keoki Williams, M.D., MPH, Center for Health Services Research and Department of Internal Medicine at Henry Ford Hospital.The study appears in this month's issue of The Journal of Clinical Endocrinology & Metabolism.