Elizabeth Antony, wife of defence minister AK Antony, will launch the third destroyer of Project 15 Alpha in Mumbai on April 1.
The destroyer has been built by the Mazagon Dock Limited for the Indian Navy.
The defence minister, Chief of Naval Staff Admiral Nirmal Verma, and south Mumbai Milind Deora would also be present, Navy sources said.
The Kolkata-class destroyers have been in Mazgaon dock in Mumbai under the code name of Project 15 Alpha.
Aimed at adding a new dimension to the country's naval warfare, India has launched the indigenous warship with enhanced stealth features and land-attack capabilities.
"Project 15 A, although conceived as a follow-on of the earlier Delhi class, has major advances in its weapons and sensors and is technologically far more superior," the sources said.