La Liga leaders Barcelona have hit a familiar mid-season slump as a congested calendar has taken its toll on their squad, and coach Ernesto Valverde must decide whether to rest key personnel for Saturday's trip to fourth-placed Sevilla.
Barca have a seven-point lead over Atletico Madrid at the top of the standings and are nine ahead of great rivals Real Madrid, giving their coach breathing room to shuffle his pack as they chase both European and domestic glory.
The Catalans are in control of their own destiny in the Champions League, but a disappointing goalless draw at Olympique Lyonnais means they must defeat the French side in the return leg to advance.
Earlier on Sunday, Atletico will try to tighten their grip on second place when they take on struggling Villarreal - a team coach Diego Simeone has never beaten since he took charge in 2011.
Athletic Bilbao host Eibar in a Basque derby on Saturday.
