The teen has lesss than 12 months to live according to her doctors.
With more than 39 million views for her YouTube blog, Talia Joy Castellano has made it to covergirl and has now become a fashion designer.
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At the tender age of 13, Castellano hails from Orlando, Florida and has terminal cancer. But nothing stops this teenager from achieving her dream as she is all set to launch a clothing collection for teenagers with Los Angeles-based designer, Urbana Chappa.
The duo met earlier this month to create the line and plan on launching their apparel brand in the coming weeks.
Chappa who runs a womenswear label called Maison De Urbana, decided to help fulfill Talia's dream of becoming a fashion designer after hearing her inspirational story on the Ellen DeGeneres show.
The fashion designer flew to Florida on April 15 to meet Talia at the Arnold Palmer Hospital for Children in Orlando and help bring her design ideas to life.
Talia was first diagnosed with stage four neuroblastoma cancer, a tumour that develops from nerve tissue in infants and children, on February 14, 2007 when she was seven-years-old.
Following chemotherapy, surgery and radiation Talia was cancer-free for a year but in September 2008, doctors found the disease had spread to a small lymph node near her heart.
For the next four years she received various treatments, but after periods the cancer kept on returning to other parts of her body.
In 2012, Talia had neuroblastoma and leukemia at the same time.
Doctors suggested a bone marrow transplant as a possible remedy but Talia decided to forgo another painful surgery and enjoy her remaining days.
Interestingly Chappa herself is a cancer survivour as she was diagnosed with breast cancer at the age of 19 but successfully overcame the disease.
Talia and Chappa have named their clothing brand That Bald Chick, in reference to Talia's hairless appearance on the Ellen Show where the host complimented the teen for her outlook on life.
In one of her YouTube tutorials the Talia explains that she doesn't wear a wig because they make her feel 'fake' and is 'just not me'.
Instead she uses make-up as a confidence booster which she teachers people to use via her channel on the video sharing space.
All proceeds from sales of Talia's clothing range will go to her family who face sky-high medical bills.
Doctors estimated last year that Talia had around four to 12 months left to live.