At least 21 people were killed and 112 wounded in shelling in the eastern Ukrainian city of Kharkiv in the last 24 hours, regional governor Oleg Synegubov said on Wednesday.

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The authorities have said Russian missile attacks hit the centre of Ukraine's second-largest city, including residential areas and the regional administration building.

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Meanwhile, Russia's defence ministry said on Russian armed forces have captured the southern Ukrainian city of Kherson on Wednesday, RIA news agency reported.