Syrian state news agency SANA, quoting a Damascus police source, said on Friday there were reports of an explosion in a police station in the Midan neighbourhood of Damascus.
Syrian state television said a young girl of about nine years of age blew herself up on Friday in a police station in the Midan neighbourhood of Damascus.
State-run Ikhbariya news channel showed blurred images of what looked like a blackened girl's head in a blanket, and scenes of destruction inside what it said was the police station.
A witness in the area of the blast said a young girl entered the police station and, after asking to go to the toilet, blew herself up.
Observatory head Rami Abdel Rahman told AFP that one woman was killed in the blast, but it remained unclear whether she was a suicide bomber or a bystander. Although rebel groups have fired rockets and mortar rounds into the capital, explosions inside the city itself are rare.
According to pro-government daily Al-Watan, the blast left "the female suicide bomber dead and wounded three police officers from the station".
In early 2012, a suicide bomber killed 26 people when he blew himself up in Midan. More than 310,000 people have died since Syria's conflict broke out in 2011.
(With PTI inputs.)